ISRG vs SYK
Intuitive Surgical and Stryker, side by side.
Prices and company dataas of yesterday's close
- ISRGBuy more19%
Intuitive Surgical's report on Oct 20 beat profit forecasts by 19%, and its sales grew 20% over the past year.
- SYKBuy moresales growth, past year7.9%
Stryker's sales grew 7.9% over the past year, but the stock fell 6.2% over the past five trading days, in step with other medical device makers (down 4.2%).
Percent return
- ISRG−21.43%
- SYK−11.38%
Nov 11, 2025 to Nov 11, 2026
Where they differ
- Company size: ISRG $127B, SYK $135B.
- Sales growth, 1 yr: ISRG +20%, SYK +7.9%. ISRG is ahead.
- Price for $1 of next year's profit: ISRG $38, SYK $20. SYK is ahead.
- Profit per $1 of sales: ISRG 32¢, SYK 24¢. ISRG is ahead.
- Cash minus debt: ISRG +$4.04B, SYK −$12.2B. ISRG is ahead.
- Price change, 1 yr: ISRG −21%, SYK −11%. SYK is ahead. S&P 500 +12%.
- How much the price swings: ISRG 46%, SYK 41%. SYK is ahead.
ISRG: faster sales growth
Our pick of these: Intuitive Surgical
Sales growth +20.4% vs +7.9%
ISRG +20.4%, SYK +7.9%.Forward P/E per point of sales growth 1.83 vs 2.59
ISRG 1.83, SYK 2.59.+12.2% to the average analyst target, vs +5.9%
ISRG +12.2%, SYK +5.9%.Where it loses: SYK has a better past year, −11.4% vs −21.4%
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Prices as of yesterday, 3:59 PM ET. A view, not advice.